Daniel A. Fletcher | Associate Professor, Department of Bioengineering
Faculty Scientist, Lawrence Berkeley National Laboratory
Deputy Division Director, Physical Biosciences Division, LBL and Synthetic Biology Engineering Research Center 608B Stanley Hall
mailcode: 1762
(510) 643-5624
fax: (510) 642-5835
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http://fletchlab.berkeley.edu | |
Joined the UC Berkeley Faculty in 2002 Research Interests
My laboratory studies the mechanics and dynamics of cell movements on the purified protein, single cell, and tissue levels. For these studies, we are developing new instruments to quantify cell and molecular mechanics based on optical microscopy, force microscopy, and microfabrication.
Education 2002 Postdoctoral Fellow, Stanford University, Biochemistry
2001 Ph.D., Stanford University, Mechanical Engineering
1997 D.Phil., Oxford University, Engineering Science
1994 B.S.E., Princeton University, Mechanical & Aerospace Engineering Major Awards 2005 Hellman Faculty Fund Award, UC Berkeley
2004 National Science Foundation CAREER Award
2004 National Collegiate Inventors and Innovators E-Team Award
2003 UC Berkeley Presidential Chair Fellow
2001 National Inventors Hall of Fame Collegiate Inventors Award
1996 National Science Foundation Graduate Research Fellowship
1995 American Society of Mechanical Engineering Arthur L. Williston Medal
1994 Rhodes Scholarship Professional Experience 2007-present Associate Professor, Bioengineering, UC Berkeley
2002-2007 Assistant Professor, Bioengineering, UC Berkeley
2003-present Faculty Scientist, Physical Biosciences, Lawrence Berkeley National Laboratory
2003-present Member, Nanoscale Science & Engineering Graduate Group, UC Berkeley
2002-present Member, Bioengineering Graduate Group, UC Berkeley & UCSF
2002-present Member, Biophysics Graduate Group, UC Berkeley
2002-present Faculty Affiliate, QB3, UC Berkeley Selected Publications O. Chaudhuri, S. H. Parekh, and D. A. Fletcher, “Reversible stress-softening of dendritic actin networks”, Nature, vol. 445, no. 7125, pp. 295-298, 2007.
W. A. Lam, M. J. Rosenbluth, and D. A. Fletcher, “Chemotherapy exposure increases leukemia cell stiffness”, Blood, [Epub ahead of print], Dec 19, 2006.
C. M. Nelson, M. M. van Duijn, J. L. Inman, D. A. Fletcher, and M. J. Bissell, “Tissue geometry determines sites of branching morphogenesis in organotypic cultures”, Science, vol. 314, no. 5797, pp. 298-300, 2006.
A. P. Liu and D. A. Fletcher, “Actin polymerization serves as a membrane domain switch in model lipid bilayers”, Biophysical Journal, vol. 91, no. 11, pp. 4064-70, 2006.
S. H. Parekh, O. Chaudhuri, J. A. Theriot, and D. A. Fletcher, “Loading history determines the velocity of actin network growth”, Nature Cell Biology, vol. 7, no. 12, pp. 1119-1123, 2005.
J. W. Shaevitz, J. Y. Lee, and D. A. Fletcher, “Spiroplasma swim by a processive change in body helicity”, Cell, vol. 122, pp. 941-945, 2005.
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