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Christopher Voigt

 

Assistant Professor, Pharmaceutical Chemistry
Core Member, UCB/UCSF Graduate Group in Bioengineering

408C Beyer's Hall
mailcode: 2540
(415) 502-7050
fax:
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http://www.voigtlab.ucsf.edu

Membership effective July 2006

Research Interests

Synthetic Biology, Biotechnology, Genetic Engineering

Research Summary

We are developing a basis by which cells can be programmed like robots to perform complex, coordinated tasks for pharmaceutical and industrial applications. We are engineering new sensors that give bacteria the senses of touch, sight, and smell. Genetic circuits - analogous to their electronic counterparts - are built to integrate the signals from the various sensors. Finally, the output of the gene circuits is used to control cellular processes. We are also developing theoretical tools from statistical mechanics and non-linear dynamics to understand how to combine genetic devices and predict their collective behavior.

Selected Publications

Anderson, J. C., Clarke, E. J., Arkin, A. P., Voigt, C. A. (2005) Environmentally Controlled nvasion of Cancer Cells by Engineered Bacteria, Journal of Molecular Biology, 335: 619-627. Levskaya, A., Chevalier, A.A., Tabor, J.J., Simpson, Z.B., Lavery, L.A., Levy, M., Davidson, E.A., Scouras, A., Ellington, A.D., Marcotte, E.M., and Voigt, C.A. (2005) Engineering E. coli to see light, Nature, 24: 441-442.

 

 

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