Susan Noworolski

Research Interests

Magnetic Resonance Imaging and Spectroscopy, Image Magnetic Resonance Imaging and Spectroscopy, Image Processing, Imaging of the Liver, Prostate Cancer and Gynecological Cancers

Research Summary

My research focus on using MR to address clinical problems in the abdomen and pelvis. Image processing and data analyses are large aspects of this work. Currently, I have projects in Dynamic contrast=enhanced MR of the prostate and MR spectroscopy of the liver. The DCE MRI data is acquired in conjunction with other MR measures of the prostate. Acquisition and evaluation of this data is being improved and assessed as compared to step-section histopathology of resected prostates. Research areas with this work inlcude image alignment, particularly for cases of tissue deformation, and mathematical modeling and presentation of the kinetic data. The liver research project is to evaluate fat in the liver in nonalcoholic fatty liver disease, due to dietary changes, and as affected by HIV and/or hepatitis C infection. Research challenges for spectroscopy of the liver include respiratory motion and data normalization.

Selected Publications

SE Moyher, DB Vigneron, SJ Nelson. Surface Coil MR Imaging of the Human Brain with an Analytical Reception Profile Correction. J of Magn Reson Im, 1995

SE Moyher, LL Wald, SJ Nelson, D Hallam, WP Dillon, D Norman, DB Vigneron. High Resolution T2-Weighted Imaging of the Human Brain Using Surface Coils and an Analytical Reception Profile Correction. J of Magn Reson Im. 1997. 

S Noworolski, S Nelson, R Henry, M Day, L Wald, J Star-Lack, D Vigneron. High Spatial Resolution 1H MRSI and Segmented MRI of Cortical Gray Matter and Subcortical White Matter in THree Regions of the Human Brain. Magn Reson Med. 1999.

SM Noworolski, NJ Fischbein, MJ Ka[lan, Y Lu, SJ Nelson, LC Carvajal, RG Henry. Challenges in Dynamic Contrast-Enhanced MR Imaging of Cervical Lymph Nodes to Detect Metastatic Disease. J of Magn Reson Im. 2003.

SM Noworolski, RG Henry, DB Vigneron, J Kurhanewicz. Dynamic Contrast-Ehanced MRI in Normal and Abnormal Prostate Tissues as Defined by Biopsy, MRI and 3D MRSI. Magn Reson Med. 2005.

SM Noworolski, JC Crane, DB Vigneron, J Kurhanewicz. A Clinical Comparison of Rigid and Inflatable Endorectal Coil Probes for MRI and 3D MRSI of the Prostate. Journal of Magn Reson Imaging. In Press. 2008.

SM Noworolski, DB Vigneron, AP Chen, J Kurhanewicz. Combined Dynamic Contrast-Enhanced MRI and MR Diffusion to Distinguish Between Glandular and Stromal Prostatic Tissues. Magn Reson Im. In Press. 2008.