Thomas F. Budinger

Professor in the Graduate School, Bioengineering Professor Emeritus, Electrical Engineering & Computer Science, UCB and Radiology, UCSF Senior Faculty Scientist, Department of Functional Imaging, LBL Core Member, UCB/UCSF Graduate Group in Bioengineering 481 Evans Hall mailcode: MC 1762 (510) 486 5435 fax: (510) 486 4768 This e-mail address is being protected from spambots. You need JavaScript enabled to view it http://bioeng.berkeley.edu/budinger/ Membership effective July 1983

Research Interests

Medical imaging instrumentation and data analysis methods development are the main focus of research from the standpoints of innovations and new techniques.Human physiology investigations using tools of imaging and wireless biomonitoring is a secondary focus..

Research Summary

Two areas  of biomedical research are neurodegeneration (e.g. Alzheimer's disease and Parkinson's disease), and heart disease (e.g., atherosclerosis and heart failure). My research is directed toward development of instrumentation and molecular chemistry probes to better understand the mechanisms of these diseases. The instrumentation development include positron and single photon computed tomography, magnetic resonance imaging and spectroscopy developments, wireless biomonitoring, and methods to quantitate the compliance of the vascular system. Applied mathematics research is in the area of the inverse problem with the objective of improving reconstruction tomography with noisy data. Nuclear chemistry developments are directed toward improving radionuclide availability through inventions of methods to produce positron emitters in small clinics. The applications of instrumentation and chemical probes include gene therapy, stem cell research and molecular imaging of the brain and the heart. Novel approaches to considering ethical dilemmas and to the incorporation of ethics in emerging technologies is a major teaching interest, in addition the topic  of biomedical imaging instrumentation  and methods.

Selected Publications

Budinger TF. Biomonitoring with wireless communications. Annu Rev Biomed Eng, 5:383-412, 2003.

Maltz JS and Budinger TF. Evaluation of arterial endothelial function using transit times of artificially induced pulses. Physiol Meas 26(3):293-307, 2005.

Qi J, Huber JS, Huesman RH, Moses WW, Derenzo SE and Budinger TF. Septa design for a prostate specific PET camera. IEEE Trans Nucl Sci 52(1):107-113, February 2005. 

Huber JS, Choong WS, Moses WW, Qi J, Hu J, Wang GC, Wilson D, Oh S, Huesman RH, Derenzo SE and Budinger TF. Initial results of a postiron tomograph for prostate imaging. IEEE Trans Nuc Sci. 2006

Nikanjam M, Blakely EA, Bjornstad KA, Shu, X, Budinger TF, Forte TM. Synthetic nano-lowdensity lipoprotein as targeted drug delivery vehicle for glioblastoma multiforma. International J. Pharmaceutics. 328: 86-94, 2007.

Ethics in Emerging Technologies: Scientific Facts and Moral Challenges. Budinger TF. And Budinger MD  John Wiley & sons 496 pp., 2006.