Computational Biology, Bioinformatics, Genomics Computational biology ("Comp.Bio.") is a rapidly developing field. Bioinformatics/Computational Biology research draws students from diverse backgrounds including applied mathematics, informatics, statistics, computer science, physics, chemistry, and biology to study biological composition, structure, function, and evolution at the molecular, cellular, and systems levels. The resulting vibrant and interactive community of researchers spans multiple length scales, time scales and academic disciplines, and the rich curriculum and collaborative, multidisciplinary research environment is fertile ground for training of students in this new and growing discipline. Building on foundations of computer science, mathematics and molecular biology, Comp.Bio. in the graduate group addresses diverse questions: the simulation of molecular and cellular systems; the organization of data from phylogenomics, metagenomics and molecular ecology projects; new challenges in molecular imaging; and new medical technologies. Examples of research areas include molecular modeling of proteins and their complexes, designing new proteins and protein interfaces, mapping the evolution of proteins and enzymatic function, statistical analysis of genomes to identify transcription factor binding sites, mining protein expression data to reveal drug targets in pathogen genomes, and studying the genetic variation in human membrane transporters. In many cases, several laboratories collaborate to tackle multiple facets of these challenging problems. A growing emphasis is being placed on the interfaces between bioinformatics and biophysics, systems biology, chemical biology, pharmacogenomics, human genetics, and bioengineering. Computational Biology faculty in the Graduate Group: David Agard, UCSF, Core Member Computational Biology, Bioinformatics, Genomics; Biomedical Imaging J. Christopher Anderson, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Tissue Engineering Adam Arkin, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Tissue Engineering Patricia Babbitt, UCSF, Core Member Computational Biology, Bioinformatics, Genomics Harvey W. Blanch, UCB, Affiliate Computational Biology, Bioinformatics, Genomics; Biomaterials; Tissue Engineering Steven E. Brenner, UCB, Core Member Computational Biology, Bioinformatics, Genomics John Canny, UCB, Core Member Computational Biology, Bioinformatics, Genomics Michelle Chang, UCB, Core Member Computational Biology, Bioinformatics, Genomics Jhih-Wei Chu, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Biomaterials; Biomechanics Maurice Cohen, UCSF, Affiliate Computational Biology, Bioinformatics, Genomics; Biomedical Imaging; Biomedical Instrumentation; Neural Systems Analysis Irina Conboy, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Biomaterials; Tissue Engineering Deborah Dean, UCSF, Affiliate Computational Biology, Bioinformatics, Genomics; BioMEMS, Nanotechnology, Robotics; Tissue Engineering Thomas E. Ferrin, UCSF, Core Member Computational Biology, Bioinformatics, Genomics Grant Gullberg, UCB, Affiliate Computational Biology, Bioinformatics, Genomics; Biomechanics; Biomedical Imaging; Biomedical Instrumentation Teresa Head-Gordon, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Biomaterials; Biomechanics Ian Holmes, UCB, Core Member Computational Biology, Bioinformatics, Genomics Donna Hudson, UCSF, Core Member Computational Biology, Bioinformatics, Genomics; Biomedical Imaging; Biomedical Instrumentation; Neural Systems Analysis C. Anthony Hunt, UCSF, Core Member Computational Biology, Bioinformatics, Genomics; Drug Delivery; Tissue Engineering Thomas James, UCSF, Core Member Computational Biology, Bioinformatics, Genomics; Biomedical Imaging; Drug Delivery Don L. Jewett, UCSF, Affiliate Computational Biology, Bioinformatics, Genomics; Biomedical Imaging; Biomedical Instrumentation; Neural Systems Analysis; Vision Richard Karp, UCB, Core Member Computational Biology, Bioinformatics, Genomics Jay Keasling, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Biomaterials Hao Li, UCSF, Core Member Computational Biology, Bioinformatics, Genomics; Biomechanics; Tissue Engineering Han Lim, UCB, Core Member Computational Biology, Bioinformatics, Genomics Mohammad Mofrad, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Biomechanics; Tissue Engineering Lior Pachter, UCB, Core member Computational Biology, Bioinformatics, Genomics Jean Pouliot, UCSF, Core Member Computational Biology, Bioinformatics, Genomics; Biomedical Imaging; Biomedical Instrumentation Boris Rubinsky, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Biomedical Imaging; Biomedical Instrumentation; BioMEMS, Nanotechnology, Robotics; Drug Delivery; Neural Systems Analysis; Tissue Engineering David Schaffer, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Biomaterials; Drug Delivery; Tissue Engineering Greg Simpson, UCSF, Affiliate Computational Biology, Bioinformatics, Genomics; Biomedical Imaging; Biomedical Instrumentation; Neural Systems Analysis Kimmen Sjölander, UCB, Core Member Computational Biology, Bioinformatics, Genomics Vernon Smith, UCSF, Affiliate Computational Biology, Bioinformatics, Genomics; Biomedical Imaging Robert Spear, UCB, Core Member Computational Biology, Bioinformatics, Genomics; Biomedical Imaging Michael Stryker, UCSF, Core Member Computational Biology, Bioinformatics, Genomics; Biomedical Imaging; Neural Systems Analysis; Vision Colin Studholme, UCSF, Affiliate Computational Biology, Bioinformatics, Genomics; Biomedical Imaging Christopher Voigt, UCSF, Core Member Computational Biology, Bioinformatics, Genomics