Professors Niren Murthy and Irina Conboy are lead authors on a new study which demonstrates the delivery of CRISPR genome-editing molecules via nanoparticles rather than via viruses. They show that CRISPR components can be packaged around individual gold nanoparticles and wrapped in a protecting polymer, and that the nanoparticles deliver the CRISPR components into a wide variety of cells efficiently.
Prof Irina Conboy’s lab has pioneered a method that paves the way to characterization of proteome alterations in vivo, whether imposed by age or disease.This research was published in Nature Communications.
Professor Amy Herr’s lab has been awarded an R33 grant as part of the 2017 Beau Biden Cancer Moonshot Initiative. The grant will fund their work on “Advanced Cancer Classification via Single-Cell Electrophoretic Cytopathology.”
The National Cancer Moonshot works to accelerate research efforts by enhancing data access and facilitating collaborations among researchers, doctors, philanthropies, patients, patient advocates, and biotechnology and pharmaceutical companies. The initiative aims to bring about a decade’s worth of advances in five years.
Professor Sanjay Kumar’s lab collaborated to show how identical embryonic skin cells organize to produce follicles and feathers, based on resistance from the materials underlying the skin. This could lead to more practical use of stem cells to produce skin graft materials. The work was conducted with Amy Shyer, a Miller postdoctoral fellow, and visiting scholar Alan Rodrigues, of Professor Harland’s lab, and BioE PhD student Elena Kassianidou.
Professor Niren Murthy, in partnership with School of Public Health Professor Lee Riley, has be awarded a three-year R33 grant from the National Institutes of Health, National Institute of Allergy and Infectious Diseases.
Professor Amy Herr’s microfluidic liquid biopsies are featured in the latest Promise of Berkeley magazine.
Professor Michael Yartsev has received a Fay/Frank Seed Grant from the Brain Research Foundation, which provides start-up monies for new research projects in the field of neuroscience.
Researchers in Prof. Irina Conboy’s lab found that viral infections turn down the intensity of a key oxytocin receptor linked to healing and health of skeletal muscle and bone, mental well-being and prevention of obesity. The pathway was recently shown to be needed for muscle maintenance and regeneration, which declines with age.
Professor Steve Conolly’s lab continues it’s push to make Magnetic Particle Imaging a reality with four first-in-animal demonstrations published this year.