BioE Seminars

Spring 2017 Bioengineering Seminar Series

Wednesdays, 12:00 noon-1:00 pm
290 Hearst Memorial Mining Building
(please note NEW ROOM LOCATION)

Next Seminar:


Chris Vollmers
Assistant Professor of Biomolecular Engineering
UC Santa Cruz

​Wednesday, March 22
12noon – 1:00pm
290 Hearst Mining Building

“Investigating B cell diversity — Using Nanopore Technology to Improve Single Cell RNAseq.”

Recent advances in molecular biology protocols and sequencing technology have made it possible to analyze the entire transcriptomes of single cells. Applying this single cell RNAseq technology to B and T cells has the potential to uncover the true diversity of the adaptive immune system. However, Illumina sequencing technology, the current gold standard for RNAseq analysis, is not capable to resolve many of the more complex transcript isoforms present in mammalian transcriptomes. Therefore, we have implemented both library preparation protocols and computational tools to use Oxford Nanopore Technology sequencing for the RNAseq analysis of single cells. This has allowed us to identify high diversity among B cell surface receptor isoforms that Illumina sequencing failed to resolve.

Upcoming seminars:

March 29 NO SEMINAR due to Spring Recess
April 5 Kandice Tanner
Chief, Tissue Morphodynamics Unit
National Institutes of Health
April 12 Polly Fordyce
Assistant Professor of Genetics and Bioengineering
Fellow, ChEM-H Institute
Stanford University
April 19 Ahmad (Mo) Khalil
Innovation Career Development Professor
Assistant Professor of Biomedical Engineering
Associate Director, Biological Design Center
Boston University
April 26 Patrick Stayton
Professor of Bioengineering
University of Washington
May 3 TBA

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View a list of past seminar speakers