BioE Seminars

Fall 2022

Wednesdays, 12:00 – 1:00 PM
290 Hearst Memorial Mining Building

Abstract:
Cadaveric allogeneic islet transplantation with concomitant chronic immunosuppression to prevent graft rejection in patients with type I diabetes (TID) has historically resulted in sustained insulin independence or reduced insulin requirements in most patients. The limited supply of human islet donors along with the challenges associated with chronic immunosuppression have restricted widespread access to islet replacement. The emergence of pluripotent stem cells as a renewable and expandable cell source for treating insulin-requiring diabetes with their capacity to differentiate into insulin-producing cells as well as CRISPR/Cas9 gene editing approaches have paved the way for addressing the major hurdles in cell therapy for treatment of TID. In this seminar, I will share our approach and progress in using gene edited cell-based therapy for treatment for TID.

Upcoming seminars

10/19:
Vivek Shenoy
Eduardo D. Glandt President’s Distinguished Professor
Center for Engineering Mechanobiology and School of Engineering and Applied Sciences, University of Pennsylvania

10/26:
Jason D. Buenrostro (via Zoom)
Assistant Professor of Stem Cell and Regenerative Biology, Harvard University

11/2:
Karthik Shekhar
Assistant Professor of Chemical and Biomolecular Engineering
UC Berkeley

DEI Seminar 11/16:
Sherilynn Black
Associate Vice Provost for Faculty Advancement
Assistant Professor of the Practice of Medical Education, Duke University

11/30:
Taher Saif
Professor, Mechanical Science and Engineering
University of Illinois at Urbana-Champaign

Don’t miss our annual Distinguished Lecture in Bioengineering and Rising Star Lecture. 

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View a list of past seminar speakers