Professor Steven Conolly’s lab is the first in the world to achieve cell tracking in vivo by magnetic particle imaging.
Authored by recent BioE Ph.D. Bo Zheng, the publication announces successful monitoring of cellular grafts with high contrast, sensitivity, and quantitativeness. The study shows 200-cell detection in vitro and in vivo monitoring of human neural graft clearance over 87 days in rat brain.
Magnetic particle imaging (MPI) directly detects the intense magnetization of iron-oxide tracers using low-frequency magnetic fields. MPI is safe, noninvasive and offers superb sensitivity, with great promise for clinical translation and quantitative single-cell tracking.
The research was conducted with Professor Steven Conolly in collaboration with Professor David Schaffer, and published in Nature Scientific Reports.