Trinh Lam, a postdoc in Amy Herr’s lab, has won the Biomicrofluidics Best Paper Award from AIP Publishing at the 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences – Micro-Total Analysis Systems (µTAS 2024).
research
Could a new medical approach fix faulty genes before birth?
Murthy lab and UC Davis have developed a unique mRNA delivery method for in-utero gene editing for neurodevelopmental conditions.
Thermostable Cas9 Enhances RNP Performance in Lung and Liver
Niren Murthy and collaborators have developed a more stable version of the Cas9 enzyme to improve delivery of CRISPR-Cas9 ribonucleoproteins (RNPs) for in vivo gene editing.
Arkin Lab receives ARPA-H award for microbiome engineering
Professor Adam Arkin has been granted an award of over $20 million from the Advanced Research Projects Agency for Health (ARPA-H) to pursue microbiome engineering to create probiotic bacterial communities that prevent and treat lung pathogens.
Delcassian receives seed funding for cancer research
Professor Derfogail Delcassian has been awarded $1 million in non-dilutive seed funding to accelerate the commercialization of her work on targeted molecular therapies for hard-to-treat cancers.
Acid-degradable lipid nanoparticles enhance the delivery of mRNA
Research published today in Nature Nanotechnology by Niren Murthy’s lab presents a new acid-degradable linker that rapidly hydrolyzes in endosomes but is stable in the blood. This development could significantly increase the efficiency of delivering mRNA through lipid nanoparticles, critical for delivering mRNA-based therapies to cells.
New recyclable adhesives can be easily adapted for medical, consumer and industrial applications
Researchers in Professor Messersmith’s lab have created a family of polymers from a new, stabilized alpha-lipoic acid, which could lead to versatile, high-performance and environmentally friendly recyclable adhesives.
Revealing the Mysteries Within Microbial Genomes
Adam Arkin’s lab has developed a new technique called, barcoded overexpression bacterial shotgun library sequencing (Boba-seq), that will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes.
Scientists Discover Next-Generation System for Programmable Genome Design
A team of researchers led by Professor Patrick Hsu has discovered the first DNA recombinase that is programmable, allowing the user to specify any desired genomic target sequence and any donor DNA molecule to be inserted. The bridge recombinase mechanism promises to expand genome editing beyond CRISPR and RNA interference (RNAi) to offer a unified mechanism for programmable DNA rearrangements. Bioengineering graduate student Nicholas Perry is also a lead author of the study, along with other researchers from the Arc Institute.