Infectious Disease
Recent news:
Professor Dan Fletcher has been elected to the National Academy of Medicine for his contributions to the mechanistic understanding of biological self-assembly and mechanotransduction, and his work developing mobile phone-based microscopy for remote diagnosis of infectious diseases. Election to the academy is considered one of the highest honors in the fields of health and medicine.
Adam Arkin has been granted an award of over $20 million from the Advanced Research Projects Agency for Health (ARPA-H) to pursue microbiome engineering to create probiotic bacterial communities that prevent and treat lung pathogens.
The Chan Zuckerberg Initiative has allocated a $4 million grant to support collaborative research by UCLA, USC and CalTech that will examine cellular behaviors, many of which play a key role in developing immunity to pathogens and disease. Dino Di Carlo, UCLA professor of bioengineering and UC Berkeley BS and PhD alumnus, will lead the team.
Lucira, a Berkeley spinout company founded by BioE alumni Debkishore Mitra and John Waldeisen, has created the first combination home test for flu and COVID to be cleared by the FDA. The agency granted emergency use authorization to the Lucira Covid-19 & Flu Test, which provides results in about 30 minutes from samples collected by a nasal swab.
In a new paper in Nature Chemical Biology, Professor Adam Arkin and collaborator Vivek Mutalik report advances in understanding phage biology that bring us closer to using these small predators to fight antibiotic-resistant bacteria.
Patrick Hsu’s lab has developed an RNA-extraction-free test for rapid viral detection using saliva via a microfluidic device. The fast, accurate, and portable prototype shows potential as a point-of-care system to support frequent, on-site molecular diagnostics. This work was the August 2022 cover story for Nature Biomedical Engineering.
A study led by Prof Patrick Hsu has identified specific proteins within our bodies that can promote or protect us from SARS-CoV-2 infections, potentially opening the door to new antiviral therapies. Notably, they showed that mucins — the main component of mucus found in the lungs — seem to help block the SARS-CoV-2 virus from entering cells.
Professor Teresa Head-Gordon will continue the machine learning COVID-19 research spurred by a 2020 Digital Transformation Institute grant, with the Midwest Antiviral Drug Discovery Center for Pathogens of Pandemic Concern, one of nine new centers announced by the National Institute of Allergy and Infectious Diseases on May 18, 2022.
Developed by former BioE postdoc Kiana Aran, the CRISPR-Chip now in use in Cardea Bio’s CRISPR-SNP-Chip has been named one of 2021’s Top 10 Innovations by The Scientist magazine. The new chip is the first device capable of detecting single base differences in DNA without generating millions of copies of the DNA first.