Cell and Tissue Engineering
Recent news:
An in-depth look at research by Professor Phil Messersmith, who draws on biology to develop cutting-edge materials for medicine. His lab creates adhesives and therapies designed to work with the human body, offering new ways to repair tissues, heal wounds and treat disease.
Professor Dan Fletcher has been elected to the National Academy of Medicine for his contributions to the mechanistic understanding of biological self-assembly and mechanotransduction, and his work developing mobile phone-based microscopy for remote diagnosis of infectious diseases. Election to the academy is considered one of the highest honors in the fields of health and medicine.
Researchers from Professor Michael Yartsev’s lab used wireless recording devices to track neural activity in Egyptian fruit bats, revealing new clues to how our long-term memories are formed.
Professor Phil Messersmith and colleagues have launched HypO2Regen Therapeutics, a startup developing novel, disease-modifying therapeutics for chronic intractable inflammatory diseases, including the first cell-free stem cell treatment that induces true regeneration of damaged tissue. Their first effort takes aim at periodontitis, which affects over 300 million people worldwide.
Michael Yartsev will receive the 2025 Richard Lounsbery Award from the National Academy of Sciences to recognize his extraordinary scientific achievement in understanding the neural basis of natural behaviors.
The Chan Zuckerberg Initiative has allocated a $4 million grant to support collaborative research by UCLA, USC and CalTech that will examine cellular behaviors, many of which play a key role in developing immunity to pathogens and disease. Dino Di Carlo, UCLA professor of bioengineering and UC Berkeley BS and PhD alumnus, will lead the team.
Professor Irina Conboy and former student Alina Su have founded a new company, Generation Lab, offering an at-home molecular aging test that analyzes a person’s biological age by assessing “biological noise” in their system. The test evaluates an individual’s risk for top health conditions and the pace of aging across 19 systems in the body, which can help physicians see where interventions may be most needed and effective.
Researchers in Professor Phillip Messersmith’s lab have demonstrated that treatment with DPCA, an enzyme inhibitor molecule shown to trigger regeneration in mammals, can protect against and repair colon damage in a mouse model of colitis. This work suggests that short-term use of this small molecule drug could someday provide a restorative therapy for patients with IBD — and a path to remission.
New work from Irina Conboy’s lab extends to humans their previous animal studies on age-specific differences in blood plasma, and establishes a novel direct measurement of biological age. Their results continue to demonstrate that aging may be driven by an excess of certain molecules and proteins, and point to potential treatments for age-related conditions.