TotalVI: A transformative algorithm

aaron streets

Researchers co-led by Professor Aaron Streets have invented a computer algorithm that uses deep learning to integrate gene and protein data about single cells that were gathered from different tissues and donors and were processed in different labs. Part of a global effort to build a Human Cell Atlas (HCA), the new algorithm will allow integration of data from different types of experiments to compile detailed protein information.

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Lareau helps detect more infectious COVID variant at Berkeley

COVID evolutionary tree

Professor Liana Lareau has been co-leading the Innovative Genomics Institute effort to monitor mutations in the SARS-CoV-2 virus in the local community. The team’s rapid sequencing turnaround is crucial for tracking the spread of new variants, including the more infectious B.1.1.7 recently detected in two cases at Berkeley.

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How water helps the substrate into the enzyme

photo of water droplet

An international research team including Professor Teresa Head-Gordon have investigated why cages can increase the catalytic activity of enclosed molecules. Using terahertz spectroscopy and complex computer simulations, they showed that water encapsulated in a tiny cage has special properties that are structurally and dynamically distinct from any known phase of water.

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Cataloging Nature’s Hidden Arsenal: Viruses that Infect Bacteria

illustration of phages attacking cell

Adam Arkin is one of the leaders of a new approach for studying which bacterial receptors phages exploit to infect cells, and what cellular mechanisms the bacteria use to respond to a phage infection. These microscopic battles have implications for medicine development, agricultural research, and climate science.

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Sanjay Kumar named AAAS Fellow

photo of Kumar

Congratulations Professor Sanjay Kumar, named to the 2020 class of Fellows of the American Association for the Advancement of Science. Kumar was recognized for his “distinguished contributions to the field of bioengineering, particularly the development of biomaterial and single-cell technologies to investigate mechanobiological signaling in health and disease.”

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Congratulations Prof Vandsburger, new Guertin Chair

Photos of Guertin and Vandsburger

Congratulations to Associate Professor Moriel Vandsburger, the first holder of our new Timothy and Karen Guertin Chair in Bioengineering. Timothy Guertin (B.S. alum, EECS) is the  former Chief Executive Officer of Varian Medical Systems, a member of the Board of Directors at Teradyne Inc., and Chair of the Global Access to Cancer Care foundation, which works to expand the availability of modern cancer care in developing countries. The Guertins are passionate supporters of biomedical research and global access to quality healthcare, and have endowed this faculty chair to provide additional support to an early career professor pursuing promising research. 

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