Posts Tagged ‘murthy’
Thermostable Cas9 Enhances RNP Performance in Lung and Liver
Niren Murthy et al. have developed a more stable version of the Cas9 enzyme to improve delivery of CRISPR-Cas9 ribonucleoproteins (RNPs) for in vivo gene editing.
Read MoreAcid-degradable lipid nanoparticles enhance the delivery of mRNA
Research by Niren Murthy’s lab presents a new acid-degradable linker that rapidly hydrolyzes in endosomes but is stable in the blood, which could significantly increase the efficiency of delivering mRNA-based therapies to cells.
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