Professor Iain Clark, in partnership with graduate program faculty member Adam Abate, was able to analyze single cells harboring latent HIV using a technique that isolates single, infected cells as tiny amounts of blood move through their microfluidic devices. Their work was featured in Science news.
New research from the Conboy Lab, highlighted in New Scientist magazine, has demonstrated that transfusing young mice with blood from older rodents quickly triggers ageing in the young, suggesting that cellular ageing isn’t just a case of wear and tear. This is one step closer to potential anti-ageing treatments and builds on years of aging research from Professor Irina Conboy.
A study led by Prof Patrick Hsu has identified specific proteins within our bodies that can promote or protect us from SARS-CoV-2 infections, potentially opening the door to new antiviral therapies. Notably, they showed that mucins — the main component of mucus found in the lungs — seem to help block the SARS-CoV-2 virus from entering cells.
New research led by Professor Jay Keasling took inspiration from an extraordinary antifungal molecule made by Streptomyces bacteria to develop a totally new type of fuel that has projected energy density greater than the most advanced heavy-duty fuels used today, including the rocket fuels used by NASA.
In a study published in Nature, a team of researchers in the lab of Professor Michael Yartsev studied neural activity in the hippocampus of freely flying bats and found that the neural codes remained unchanged over days and weeks. The discovery that these GPS-like neural codes remain stable over time has upended previous research and may further our understanding of diseases like Alzheimer’s.
A study led by Professor Emeritus David Rempel and the environmental non-profit group Cool the Earth tested the functionality of 657 EVSE (electric vehicle service equipment) connectors at all 181 open public, non-Tesla charging stations in the Bay area. The study found that 27% were nonfunctional, a concerning issue for the widespread adoption of electric vehicles.
Research by BioE PhD student Aaron Berliner and Prof Adam Arkin shows that photovoltaics could provide all the power needed for an extended mission to Mars, or even a permanent settlement there. The authors are members of the Center for the Utilization of Biological Engineering in Space (CUBES), led by Adam Arkin.
Engineered biomaterials are increasingly used to expand and differentiate stem cells for technological and therapeutic applications. A major open question in the field is how the mechanical properties of material scaffolds regulate stem cell differentiation, especially in complex 3D geometries like those found in tissue. In a collaborative study published in Science Advances, the labs of Sanjay Kumar and David Schaffer have discovered a 3D-specific molecular mechanism through which mechanical inputs act through the transcription factor Egr1 to determine how efficiently neural stem cells turn into neurons.
Nearly 20 years after the sequencing of the human genome, a large team of researchers has finally filled in the remaining few percent of unsequenced DNA, providing the first complete, gapless human genome. First author of many of the suite of papers is Nicolas Altemose, 2021 bioengineering PhD and current postdoc with co-author Professor Aaron Streets.