Gene Editing
Recent news:
Professor Liana Lareau is recognized for her revolutionary approach to treat retinitis pigmentosa and other dominant genetic diseases by combining CRISPR prime editing with machine learning.
Research led by Professor Patrick Hsu has produced Evo 2, the largest AI model in biology to date, which can accurately predict the effects of all types of genetic mutations.
Patrick Hsu’s breakthrough discovery of bridge RNA gene editing tools is discussed on WebMD, with contributions from BioE alumnus Connor Tou.
Adam Arkin has been granted an award of over $20 million from the Advanced Research Projects Agency for Health (ARPA-H) to pursue microbiome engineering to create probiotic bacterial communities that prevent and treat lung pathogens.
Murthy lab and UC Davis have developed a unique mRNA delivery method for in-utero gene editing for neurodevelopmental conditions.
Niren Murthy et al. have developed a more stable version of the Cas9 enzyme to improve delivery of CRISPR-Cas9 ribonucleoproteins (RNPs) for in vivo gene editing.
Professor Leah Guthrie works to understand how the microbiome metabolites and proteins communicate with our human cells to influence our physiology and pathophysiology. Learn more about Guthrie in this interview with QB3.
Professor Derfogail Delcassian has been awarded $1 million in non-dilutive seed funding to accelerate the commercialization of her work on targeted molecular therapies for hard-to-treat cancers.
Research by Niren Murthy’s lab presents a new acid-degradable linker that rapidly hydrolyzes in endosomes but is stable in the blood, which could significantly increase the efficiency of delivering mRNA-based therapies to cells.