October 8, 2012 –
For synthetic biology to reach its promise, the design and construction of biological systems must be as predictable as the assembly of computer hardware. An important step has been taken by bioengineering professor Adam Arkin and a team of researchers, who have developed an “adaptor” that makes the genetic engineering of microbial components easier and more predictable by converting regulators of translation into regulators of transcription in E. coli.
This groundbreaking work was published in Nature Methods, titled “An adaptor from translational to transcriptional control enables predictable assembly of complex regulation. Co-authors are Chang Liu, Lei Qi, Julius Lucks, Thomas Segall-Shapiro, Denise Wang and Vivek Mutalik.
Read more at Lawrence Berkeley Lab