Phillip Messersmith
Chair of Bioengineering, Class of 1941 WWII Memorial Chair in Bioengineering and Materials Science and Engineering
Office Address: 218 Hearst Memorial Mining Building
Email: philm@berkeley.edu
For more information, see: https://bioinspiredmaterials.berkeley.edu/
Office hours: By appointment
Research areas:
Biomaterials & Nanotechnology, Cell and Tissue Engineering
My laboratory is interested in understanding structure-property relationships in biological materials and in using this information to design biologically inspired materials for use in healthcare. Fundamental studies include single molecule and bulk biophysical studies of biointerfacial and bulk mechanochemical phenomena in biological materials, whereas our applied studies the design and synthesis of novel biomaterials for tissue repair and regeneration.
Education
- 1993 Ph.D. Department of Materials Science and Engineering, University of Illinois at Urbana
- 1987 M.S. Department of Bioengineering, Clemson University
- 1985 B.S. School of Life Sciences, University of Illinois at Urbana
Experience & Training
- 2023-present Chair, Department of Bioengineering
- 2014-present Class of 1941 Endowed Professor of Bioengineering and Materials Science and Engineering, UC Berkeley
- 2006-2014 Professor, Departments of Biomedical Engineering, Materials Science and Engineering, and Chemical and Biological Engineering, Northwestern University
- 2003-2005 Associate Professor, Departments of Biomedical Engineering and Materials Science and Engineering, Northwestern University
- 2000-2003 Assistant Professor, Department of Biomedical Engineering, Northwestern University
- 1998-1999 Assistant Professor, Department of Physical Medicine and Rehabilitation, Medical School, and Department of Biomedical Engineering, Northwestern University
- 1997-1998 Assistant Professor, Division of Biological Materials, Dental School, Northwestern University
- 1994-1997 Assistant Professor, Restorative Dentistry and Bioengineering, University of Illinois at Chicago
- 1992-1994 Postdoc Department of Materials Science and Engineering, Cornell University
Honors & Awards
- 2015 Member, National Advisory Dental and Craniofacial Research Council (NIH)
- 2014-present Class of 1941 Professor, Departments of Bioengineering and Materials Science and Engineering, UC Berkeley
- 2014 Chair of the Gordon Research Conference on Bioinspired Materials
- 2013 Clemson Award for Basic Research, Society for Biomaterials
- 2012 Fellow, International Union of Societies of Biomaterials Science and Engineering
- 2012 Co-Editor in Chief, Biomaterials Science
- 2010 Program Chair of the Annual Meeting of the Society for Biomaterials
- 2010 Fellow, Royal Society of Chemistry
- 2010 Chair of the Gordon Research Conference on Biointerface Science
- 2009 Langmuir Lecture Award Recipient, American Chemical Society, Division of Colloids and Surface Science
- 2008 Japan Society for the Promotion of Science, Visiting Research Fellowship
- 2006 MERIT Award, NIH
- 2006 Fellow, American Institute for Medical and Biological Engineering (AIMBE)
- 2003 Member, Biomaterials and Biointerfaces Study Section, NIH
- 1997 NIH First Award
2024
Pal, Subhajit; Shin, Jisoo; Defrates, Kelsey; Arslan, Mustafa; Dale, Katelyn; Chen, Hannah; Ramirez, Dominic; Messersmith, Phillip B.
Recyclable surgical, consumer, and industrial adhesives of poly(α-lipoic acid) Journal Article
In: SCIENCE, vol. 385, no. 6711, pp. 877-883, 2024, ISSN: 0036-8075.
@article{WOS:001310111200016,
title = {Recyclable surgical, consumer, and industrial adhesives of poly(α-lipoic
acid)},
author = {Subhajit Pal and Jisoo Shin and Kelsey Defrates and Mustafa Arslan and Katelyn Dale and Hannah Chen and Dominic Ramirez and Phillip B. Messersmith},
doi = {10.1126/science.ado6292},
issn = {0036-8075},
year = {2024},
date = {2024-08-01},
journal = {SCIENCE},
volume = {385},
number = {6711},
pages = {877-883},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Lam, Bonnie; Velasquez, Mark; Ogiyama, Tomoko; Godines, Kevin; Szu, Fan-Yun; Velasquez-Mao, A. J.; Alghuraibawi, Wissam; Wang, Jingshen; Messersmith, Phillip B.; Vandsburger, Moriel H.
Imaging of adeno-associated viral capsids for purposes of gene editing using CEST NMR/MRI Journal Article
In: MAGNETIC RESONANCE IN MEDICINE, vol. 92, no. 2, pp. 792-806, 2024, ISSN: 0740-3194.
@article{WOS:001206361000001,
title = {Imaging of adeno-associated viral capsids for purposes of gene editing
using CEST NMR/MRI},
author = {Bonnie Lam and Mark Velasquez and Tomoko Ogiyama and Kevin Godines and Fan-Yun Szu and A. J. Velasquez-Mao and Wissam Alghuraibawi and Jingshen Wang and Phillip B. Messersmith and Moriel H. Vandsburger},
doi = {10.1002/mrm.30058},
issn = {0740-3194},
year = {2024},
date = {2024-08-01},
journal = {MAGNETIC RESONANCE IN MEDICINE},
volume = {92},
number = {2},
pages = {792-806},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Refaei, Roeya; Lee, Kyueui; Lee, Goun Amy; Demian, Paul; Mansouri, Fouad El; Messersmith, Phillip B.; Lamrani, Mouad; Khaddor, Mohamed; Allali, Nabil
Functionalized Surface Coatings for Rigid Contact Lenses Journal Article
In: JOURNAL OF FUNCTIONAL BIOMATERIALS, vol. 15, no. 6, 2024.
@article{WOS:001255835200001,
title = {Functionalized Surface Coatings for Rigid Contact Lenses},
author = {Roeya Refaei and Kyueui Lee and Goun Amy Lee and Paul Demian and Fouad El Mansouri and Phillip B. Messersmith and Mouad Lamrani and Mohamed Khaddor and Nabil Allali},
doi = {10.3390/jfb15060154},
year = {2024},
date = {2024-06-01},
journal = {JOURNAL OF FUNCTIONAL BIOMATERIALS},
volume = {15},
number = {6},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Defrates, Kelsey G.; Tong, Elaine; Cheng, Jing; Heber-Katz, Ellen; Messersmith, Phillip B.
A Pro-Regenerative Supramolecular Prodrug Protects Against and Repairs Colon Damage in Experimental Colitis Journal Article
In: ADVANCED SCIENCE, vol. 11, no. 13, 2024.
@article{WOS:001146377200001,
title = {A Pro-Regenerative Supramolecular Prodrug Protects Against and Repairs
Colon Damage in Experimental Colitis},
author = {Kelsey G. Defrates and Elaine Tong and Jing Cheng and Ellen Heber-Katz and Phillip B. Messersmith},
doi = {10.1002/advs.202304716},
year = {2024},
date = {2024-04-01},
journal = {ADVANCED SCIENCE},
volume = {11},
number = {13},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2023
Ciccia, Nicodemo R.; Shi, Jake X.; Pal, Subhajit; Hua, Mutian; Malollari, Katerina G.; Lizandara-Pueyo, Carlos; Risto, Eugen; Ernst, Martin; Helms, Brett A.; Messersmith, Phillip B.; Hartwig, John F.
Diverse functional polyethylenes by catalytic amination Journal Article
In: SCIENCE, vol. 381, no. 6665, pp. 1433-1440, 2023, ISSN: 0036-8075.
@article{WOS:001100656800035,
title = {Diverse functional polyethylenes by catalytic amination},
author = {Nicodemo R. Ciccia and Jake X. Shi and Subhajit Pal and Mutian Hua and Katerina G. Malollari and Carlos Lizandara-Pueyo and Eugen Risto and Martin Ernst and Brett A. Helms and Phillip B. Messersmith and John F. Hartwig},
doi = {10.1126/science.adg6093},
issn = {0036-8075},
year = {2023},
date = {2023-09-01},
journal = {SCIENCE},
volume = {381},
number = {6665},
pages = {1433-1440},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Shi, Jake X.; Ciccia, Nicodemo R.; Pal, Subhajit; Kim, Diane D.; Brunn, John N.; Lizandara-Pueyo, Carlos; Ernst, Martin; Haydl, Alexander M.; Messersmith, Phillip B.; Helms, Brett A.; Hartwig, John F.
Chemical Modification of Oxidized Polyethylene Enables Access to Functional Polyethylenes with Greater Reuse Journal Article
In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 145, no. 39, pp. 21527-21537, 2023, ISSN: 0002-7863.
@article{WOS:001070275700001,
title = {Chemical Modification of Oxidized Polyethylene Enables Access to
Functional Polyethylenes with Greater Reuse},
author = {Jake X. Shi and Nicodemo R. Ciccia and Subhajit Pal and Diane D. Kim and John N. Brunn and Carlos Lizandara-Pueyo and Martin Ernst and Alexander M. Haydl and Phillip B. Messersmith and Brett A. Helms and John F. Hartwig},
doi = {10.1021/jacs.3c07186},
issn = {0002-7863},
year = {2023},
date = {2023-09-01},
journal = {JOURNAL OF THE AMERICAN CHEMICAL SOCIETY},
volume = {145},
number = {39},
pages = {21527-21537},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Avilla-Royo, Eva; Seehusen, Frauke; Devaud, Yannick R.; Rodriguez, Josep Monne M.; Strubing, Nele; Weisskopf, Miriam; Messersmith, Phillip B.; Vonzun, Ladina; Moehrlen, Ueli; Ehrbar, Martin; Ochsenbein-Kolble, Nicole
In vivo Sealing of Fetoscopy-Induced Fetal Membrane Defects by Mussel Glue Journal Article
In: FETAL DIAGNOSIS AND THERAPY, vol. 49, no. 11-12, pp. 518-527, 2023, ISSN: 1015-3837.
@article{WOS:000916770300001,
title = {In vivo Sealing of Fetoscopy-Induced Fetal Membrane Defects by Mussel
Glue},
author = {Eva Avilla-Royo and Frauke Seehusen and Yannick R. Devaud and Josep Monne M. Rodriguez and Nele Strubing and Miriam Weisskopf and Phillip B. Messersmith and Ladina Vonzun and Ueli Moehrlen and Martin Ehrbar and Nicole Ochsenbein-Kolble},
doi = {10.1159/000528473},
issn = {1015-3837},
year = {2023},
date = {2023-02-01},
journal = {FETAL DIAGNOSIS AND THERAPY},
volume = {49},
number = {11-12},
pages = {518-527},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2022
Kayitmazer, A. Basak; Comert, Fatih; Winter, Henning H.; Messersmith, Phillip B.
Rheology and Gelation of Hyaluronic Acid/Chitosan Coacervates Journal Article
In: BIOMOLECULES, vol. 12, no. 12, 2022.
@article{WOS:000900501900001,
title = {Rheology and Gelation of Hyaluronic Acid/Chitosan Coacervates},
author = {A. Basak Kayitmazer and Fatih Comert and Henning H. Winter and Phillip B. Messersmith},
doi = {10.3390/biom12121817},
year = {2022},
date = {2022-12-01},
journal = {BIOMOLECULES},
volume = {12},
number = {12},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Zebrowitz, Elan; Aslanukov, Azamat; Kajikawa, Tetsuhiro; Bedelbaeva, Kamila; Bollinger, Sam; Zhang, Yong; Sarfatti, David; Cheng, Jing; Messersmith, Phillip B.; Hajishengallis, George; Heber-Katz, Ellen
In: FRONTIERS IN DENTAL MEDICINE, vol. 3, 2022.
@article{WOS:001061767600001,
title = {Prolyl-hydroxylase inhibitor-induced regeneration of alveolar bone and
soft tissue in a mouse model of periodontitis through metabolic
reprogramming},
author = {Elan Zebrowitz and Azamat Aslanukov and Tetsuhiro Kajikawa and Kamila Bedelbaeva and Sam Bollinger and Yong Zhang and David Sarfatti and Jing Cheng and Phillip B. Messersmith and George Hajishengallis and Ellen Heber-Katz},
doi = {10.3389/fdmed.2022.992722},
year = {2022},
date = {2022-11-01},
journal = {FRONTIERS IN DENTAL MEDICINE},
volume = {3},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
DeFrates, Kelsey G.; Engstrom, Joakim; Sarma, Nivedina A.; Umar, Athiyya; Shin, Jisoo; Cheng, Jing; Xie, Weiran; Pochan, Darrin; Omar, Ahmad K.; Messersmith, Phillip B.
The influence of molecular design on structure-property relationships of a supramolecular polymer prodrug Journal Article
In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 119, no. 44, 2022, ISSN: 0027-8424.
@article{WOS:000964683900006,
title = {The influence of molecular design on structure-property relationships of
a supramolecular polymer prodrug},
author = {Kelsey G. DeFrates and Joakim Engstrom and Nivedina A. Sarma and Athiyya Umar and Jisoo Shin and Jing Cheng and Weiran Xie and Darrin Pochan and Ahmad K. Omar and Phillip B. Messersmith},
doi = {10.1073/pnas.2208593119},
issn = {0027-8424},
year = {2022},
date = {2022-11-01},
journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF
AMERICA},
volume = {119},
number = {44},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Wonderly, William R.; Nguyen, Tuan T. D.; Malollari, Katerina G.; DeMartini, Daniel; Delparastan, Peyman; Valois, Eric; Messersmith, Phillip B.; Helgeson, Matthew E.; Waite, J. Herbert
A multi-tasking polypeptide from bloodworm jaws: Catalyst, template, and copolymer in film formation Journal Article
In: MATTER, vol. 5, no. 6, 2022, ISSN: 2590-2393.
@article{WOS:000810939100007,
title = {A multi-tasking polypeptide from bloodworm jaws: Catalyst, template, and
copolymer in film formation},
author = {William R. Wonderly and Tuan T. D. Nguyen and Katerina G. Malollari and Daniel DeMartini and Peyman Delparastan and Eric Valois and Phillip B. Messersmith and Matthew E. Helgeson and J. Herbert Waite},
doi = {10.1016/j.matt.2022.04.001},
issn = {2590-2393},
year = {2022},
date = {2022-06-01},
journal = {MATTER},
volume = {5},
number = {6},
keywords = {},
pubstate = {published},
tppubtype = {article}
}