Five-year NIH grant supports collaborative research into rejuvenating the aging brain

Irina Conboy is one of the principal partners of a new joint study on the aging brain. Conboy, an expert in aging and blood-based rejuvenation, will partner with Yi Zuo, a professor of molecular, cell and developmental biology at UC Santa Cruz, and Philippe Mourrain, a professor of psychiatry and behavioral sciences at Stanford University. The group are looking specifically at changes to blood composition and how immune cells in the brain and central nervous system called microglia alter cognition with age, hoping to identify therapeutic interventions.

Read More

A peek inside a flying bat’s brain uncovers clues to mammalian navigation

bat

New research from Michael Yartsev’s lab shows that the ability to focus on the location where we will be in the near future may be a key characteristic of the mammalian brain’s built-in navigation system. Lab members wirelessly tracked the brain activity of Egyptian fruit bats as they flew throughout a custom flight room. The study, which opens many questions about how we process our movement in time and space, appeared online Thursday, July 8, in the journal Science.

Read More

Conboy lab continues to make strides against aging

Conboy photo

Professor Irina Conboy’s lab is a world leader in research to slow and reverse the effects of physical aging. Recently, Conboy was interviewed in a LongevityTechnology story, “Can CRISPR be used to diagnose aging?” And her work on the controversial issue of using young blood to rejuvenate was featured in the article “Young blood to…

Read More

Clark lab’s technique IDs new therapeutic targets for inflammatory autoimmunity

research illustration from publication

Cell interactions contribute to central nervous system pathology, but techniques to define these interactions are limited. In a publication in Science, Professor Iain Clark’s lab describes a new method that determines the molecular phenotypes and connections between cells in vivo. This technique allows them to identify new therapeutic targets that disrupt inflammatory crosstalk in experimental autoimmunity, and potentially, in neurologic disorders like Multiple Sclerosis. 

Read More

Arkin lab harnesses incredible bacterial ‘Homing Missiles’

artist image of a tailocin

Adam Arkin’s lab is leading research to harness tailocins – protein machines made by bacteria that are able to target and attack very specific strains of bacteria. They hope to understand and use these natural spring-powered microneedles to study the microbiome, and eventually to attack and treat harmful infections.

Read More