Irina Conboy
Professor, Bioengineering
Office Address: B108B Stanley Hall
Email: iconboy@berkeley.edu
For more information, see: https://conboylab.berkeley.edu/
Office hours: email to make an appointment
Research areas:
Biomaterials & Nanotechnology, Cell and Tissue Engineering, Systems and Synthetic Biology
Our work has been focused on establishing new paradigms in multi-tissue stem cell aging, rejuvenation and regulation by conserved morphogenic signaling pathways. One of our goals is to define pharmacology for enhancing maintenance and repair of adult tissues in vivo. The spearheaded by us heterochronic parabiosis and blood apheresis studies have established that the process of aging is reversible through modulation of circulatory milieu. Our synthetic biology method of choice focuses on bio-orthogonal non-canonical amino acid tagging (BONCAT) and subsequent identification of age-imposed and disease-causal changes in mammalian proteomes in vivo. Our drug delivery reg medicine projects focus on CRISPR/Cas9 based therapeutics for more effective and safer gene editing.