Concentration: Cell & Tissue Engineering
Work in Cell & Tissue engineering focuses on understanding and modifying the behavior of biological cells and tissues in both health and disease. This includes creating replacements for damaged tissues and body parts, and therapies to assist the body in regenerating injured or aged components.
Real-World Applications
Skin, nerve, bone, cartilage, blood vessel, and membrane replacements; replacement organs; biomimetic materials; stem cell therapies; anti-aging therapies; drug development.
News About: Cell & Tissue Engineering
Yartsev wins Richard Lounsbery Award
Michael Yartsev will receive the 2025 Richard Lounsbery Award from the National Academy of Sciences to recognize his extraordinary scientific achievement in understanding the neural basis of natural behaviors.
Alumnus Di Carlo will lead new UCLA Chan Zuckerberg Initiative cell research project
The Chan Zuckerberg Initiative has allocated a $4 million grant to support collaborative research by UCLA, USC and CalTech that will examine cellular behaviors, many of which play a key role in developing immunity to pathogens and disease. Dino Di Carlo, UCLA professor of bioengineering and UC Berkeley BS and PhD alumnus, will lead the team.
The booming business of discovering your biological age
Professor Irina Conboy and former student Alina Su have founded a new company, Generation Lab, offering an at-home molecular aging test that analyzes a person’s biological age by assessing “biological noise” in their system. The test evaluates an individual’s risk for top health conditions and the pace of aging across 19 systems in the body, which can help physicians see where interventions may be most needed and effective.
Researchers make advances toward more effective IBD therapies
Researchers in Professor Phillip Messersmith’s lab have demonstrated that treatment with DPCA, an enzyme inhibitor molecule shown to trigger regeneration in mammals, can protect against and repair colon damage in a mouse model of colitis. This work suggests that short-term use of this small molecule drug could someday provide a restorative therapy for patients with IBD — and a path to remission.
Old plasma dilution reduces human biological age
New work from Irina Conboy’s lab extends to humans their previous animal studies on age-specific differences in blood plasma, and establishes a novel direct measurement of biological age. Their results continue to demonstrate that aging may be driven by an excess of certain molecules and proteins, and point to potential treatments for age-related conditions.
Transfusing blood from an old mouse to a younger mouse causes ageing
New research from the Conboy Lab, highlighted in New Scientist magazine, has demonstrated that transfusing young mice with blood from older rodents quickly triggers ageing in the young, suggesting that cellular ageing isn’t just a case of wear and tear. This is one step closer to potential anti-ageing treatments and builds on years of aging research from Professor Irina Conboy.
The Science of Antiaging
UC Berkeley’s Irina Conboy, Ph.D., is unlocking the keys to healthy longevity
Diablo Magazine features the Conboy Lab’s research on the aging process, and ways to reverse it.
Five-year NIH grant supports collaborative research into rejuvenating the aging brain
Irina Conboy is one of the principal partners of a new joint study on the aging brain. Conboy, an expert in aging and blood-based rejuvenation, will partner with Yi Zuo, a professor of molecular, cell and developmental biology at UC Santa Cruz, and Philippe Mourrain, a professor of psychiatry and behavioral sciences at Stanford University. The group are looking specifically at changes to blood composition and how immune cells in the brain and central nervous system called microglia alter cognition with age, hoping to identify therapeutic interventions.
Conboy lab continues to make strides against aging
Professor Irina Conboy’s lab is a world leader in research to slow and reverse the effects of physical aging. Recently, Conboy was interviewed in a LongevityTechnology story, “Can CRISPR be used to diagnose aging?” And her work on the controversial issue of using young blood to rejuvenate was featured in the article “Young blood to old – where do the answers to aging lie?“ The New York Times has cited Irina and Michael Conboy’s work in their feature article, “How Long Can We Live?“