Concentration: Computational & Synthetic Biology

decorative image of data on computer screen

Synthetic and computational biologists aim to design and build novel biological functions and systems by applying engineering design principles and computational tools to biology. This includes genome editing, modeling, and analysis of large sets of genomic data.

Real-World Applications

Drug discovery, green manufacturing, agriculture, customized materials, personalized medicine, bioethics.

News About: Computational & Synthetic Biology

Keasling Named 2025 DOE/NAI Innovator of the Year

The Department of Energy and the National Academy of Inventors have honored Professor Jay Keasling with their 2025 Innovator of the Year Award, which goes to one DOE employee who has translated research into tangible impacts that have benefited society at large. Keasling is a pioneer in synthetic biology who leads a groundbreaking research program focused on engineering microorganisms to produce advanced biofuels and chemicals.

New Process Uses Microbes to Create Valuable Materials from Urine

A team led by BioE alumnus Yasuo Yoshikuni genetically modified yeast to create hydroxyapatite, a strong and lightweight material, from the elements present in urine. With lower production costs the material may now be practical for use in wastewater treatment, fertilizer manufacturing, building materials and plastic replacement.

Lareau named MTI Innovator

Professor Liana Lareau is recognized for her revolutionary approach to treat retinitis pigmentosa and other dominant genetic diseases by combining CRISPR prime editing with machine learning.

Indigenous knowledge helps biotech find new drugs. This grad student wants those companies to give back.

Bioengineering doctoral student Maria Astolfi and her colleagues argue for a new type of partnership with indigenous peoples to create a more ethical bioeconomy.

The not-so-secret life of gut bacteria

Computational modeling from Mofrad Lab gives us a peek inside these important microbial communities.

Pivot Bio is using microbial nitrogen to make agriculture more sustainable

Co-founded by BioE alumnus Karsten Temme, Pivot is bringing cleaner nitrogen to American farmland.

AI can now model and design the genetic code for all domains of life with Evo 2

Research led by Professor Patrick Hsu has produced Evo 2, the largest AI model in biology to date, which can accurately predict the effects of all types of genetic mutations.

Bridge RNAs: ‘Holy Grail’ in Next-Gen Gene Editing Tech?

Patrick Hsu’s breakthrough discovery of bridge RNA gene editing tools is discussed on WebMD, with contributions from BioE alumnus Connor Tou.

Arkin Lab receives ARPA-H award for microbiome engineering

Adam Arkin has been granted an award of over $20 million from the Advanced Research Projects Agency for Health (ARPA-H) to pursue microbiome engineering to create probiotic bacterial communities that prevent and treat lung pathogens.

Could a new medical approach fix faulty genes before birth?

Murthy lab and UC Davis have developed a unique mRNA delivery method for in-utero gene editing for neurodevelopmental conditions.